Publications

  1. Gnedeva, K, Wang, X, McGovern, MM, Barton, M, Tao, L, Trecek, T et al.. Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal. Proc. Natl. Acad. Sci. U.S.A. 2020; :. doi: 10.1073/pnas.2000175117. PubMed PMID:32482884 .
  2. Jen, HI, Hill, MC, Tao, L, Sheng, K, Cao, W, Zhang, H et al.. Transcriptomic and epigenetic regulation of hair cell regeneration in the mouse utricle and its potentiation by Atoh1. Elife. 2019;8 :. doi: 10.7554/eLife.44328. PubMed PMID:31033441 PubMed Central PMC6504235.
  3. Gnedeva, K, Hudspeth, AJ, Segil, N. Three-dimensional Organotypic Cultures of Vestibular and Auditory Sensory Organs. J Vis Exp. 2018; (136):. doi: 10.3791/57527. PubMed PMID:29912206 PubMed Central PMC6101446.
  4. Semerci, F, Choi, WT, Bajic, A, Thakkar, A, Encinas, JM, Depreux, F et al.. Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance. Elife. 2017;6 :. doi: 10.7554/eLife.24660. PubMed PMID:28699891 PubMed Central PMC5531831.
  5. Teng, CS, Yen, HY, Barske, L, Smith, B, Llamas, J, Segil, N et al.. Requirement for Jagged1-Notch2 signaling in patterning the bones of the mouse and human middle ear. Sci Rep. 2017;7 (1):2497. doi: 10.1038/s41598-017-02574-7. PubMed PMID:28566723 PubMed Central PMC5451394.
  6. Basch, ML, Brown, RM 2nd, Jen, HI, Semerci, F, Depreux, F, Edlund, RK et al.. Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. Elife. 2016;5 :. doi: 10.7554/eLife.19921. PubMed PMID:27966429 PubMed Central PMC5215100.
  7. Stojanova, ZP, Kwan, T, Segil, N. Epigenetic regulation of Atoh1 guides hair cell development in the mammalian cochlea. Development. 2016;143 (9):1632. doi: 10.1242/dev.137976. PubMed PMID:27143757 PubMed Central PMC4986168.
  8. Rainey, RN, Ng, SY, Llamas, J, van der Horst, GT, Segil, N. Mutations in Cockayne Syndrome-Associated Genes (Csa and Csb) Predispose to Cisplatin-Induced Hearing Loss in Mice. J. Neurosci. 2016;36 (17):4758-70. doi: 10.1523/JNEUROSCI.3890-15.2016. PubMed PMID:27122034 PubMed Central PMC4846672.
  9. Abdolazimi, Y, Stojanova, Z, Segil, N. Selection of cell fate in the organ of Corti involves the integration of Hes/Hey signaling at the Atoh1 promoter. Development. 2016;143 (5):841-50. doi: 10.1242/dev.129320. PubMed PMID:26932672 PubMed Central PMC4813338.
  10. Stojanova, ZP, Kwan, T, Segil, N. Epigenetic regulation of Atoh1 guides hair cell development in the mammalian cochlea. Development. 2015;142 (20):3529-36. doi: 10.1242/dev.126763. PubMed PMID:26487780 PubMed Central PMC4631768.